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mog35 55 peptide  (MedChemExpress)


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    Structured Review

    MedChemExpress mog35 55 peptide
    Mog35 55 Peptide, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 94/100, based on 6 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/mog35+55+peptide/MOG/pm42071235-43-18-25
    Average 94 stars, based on 6 article reviews
    mog35 55 peptide - by Bioz Stars, 2026-09
    94/100 stars

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    Related Articles

    Sequencing:

    Article Title: Plant defense-directed discovery of a natural anti-psoriasis agent targeting GAPDH
    Article Snippet: .. MOG35-55 peptide (amino acid sequence MEVGWYRSPFSRVVHLYRNGK-NH2, MedChemExpress, HY-P3719) dissolved in PBS at a concentration of 2 mg/mL was emulsified in an equal volume (1:1) of complete Freund’s adjuvant containing 10 mg/mL containing heat-killed Mycobacterium tuberculosis (H37Ra, Chondrex, 7027) to make an emulsion. ..

    Concentration Assay:

    Article Title: Plant defense-directed discovery of a natural anti-psoriasis agent targeting GAPDH
    Article Snippet: .. MOG35-55 peptide (amino acid sequence MEVGWYRSPFSRVVHLYRNGK-NH2, MedChemExpress, HY-P3719) dissolved in PBS at a concentration of 2 mg/mL was emulsified in an equal volume (1:1) of complete Freund’s adjuvant containing 10 mg/mL containing heat-killed Mycobacterium tuberculosis (H37Ra, Chondrex, 7027) to make an emulsion. ..

    Adjuvant:

    Article Title: Plant defense-directed discovery of a natural anti-psoriasis agent targeting GAPDH
    Article Snippet: .. MOG35-55 peptide (amino acid sequence MEVGWYRSPFSRVVHLYRNGK-NH2, MedChemExpress, HY-P3719) dissolved in PBS at a concentration of 2 mg/mL was emulsified in an equal volume (1:1) of complete Freund’s adjuvant containing 10 mg/mL containing heat-killed Mycobacterium tuberculosis (H37Ra, Chondrex, 7027) to make an emulsion. ..

    Article Title: Neuroprotective effect of Vesatolimod in an experimental autoimmune encephalomyelitis mice model.
    Article Snippet: .. For EAE induction, C57BL/6J mice were subcutaneously immunized with 250 μg MOG35–55 peptide (MCE, USA) in complete Freund’s adjuvant (Chondrex, USA) that contained 5 mg/mL of heat-killed Mycobacterium tuberculosis (H37RA). .. 400 ng Pertussis toxin (List Biological Laboratories Inc, USA) was administered at 0 h and after 48 h via intraperitoneal (IP) injection.

    Article Title: An unrecognized mechanism of neuroprotection by microglial TIA1-mediated stress granules to prevent neuroinflammation and demyelination in experimental autoimmune encephalomyelitis mice through sequestering ApoE mRNA.
    Article Snippet: .. Briefly, female mice weighing between 15~20 g were anesthetized and subsequently subcutaneously immunized with 200 μg of emulsified MOG35-55 peptide (dissolved in double-distilled water, HY-P1240A, MCE) mixed in a 1:1 ratio with Complete Freund’s Adjuvant (CFA) containing 8 mg/mL of Mycobacterium tuberculosis (H37RA strain, Difco, USA). .. Following immunization, these mice received intraperitoneal injections of 300 ng of pertussis toxin (PTX, Sigma, dissolved in PBS) on days 0 and 2.

    Article Title: Neuroprotective Effect of Vesatolimod in an Experimental Autoimmune Encephalomyelitis Mice Model
    Article Snippet: .. EAE Induction To induce EAE, male C57BL/6J mice (9 weeks old, 22 ± 2 g) were immunized with 250 μg MOG35 − 55 peptide (MCE, USA) emulsi ed in complete Freund’s adjuvant (Chondrex, USA) that contained 5 mg/mL Page 4/19 of heat-killed Mycobacterium tuberculosis (H37RA). .. 400 ng Pertussis toxin (List Biological Laboratories Inc, USA) was administered intraperitoneally at 0 h and after 48 h. Clinical symptoms were scored from the day of immunization as follows(Lu et al. 2020): 0, no symptoms; 0.5, partial limp tail; 1, complete limp tail; 1.5, hind limb ataxia; 2, hind limb paresis; 2.5, partial hind limb paralysis; 3, complete hind limb paralysis; 3.5, hind limb paralysis and fore limb paresis; 4, hind and fore limb paralysis; 5, moribund.

    Article Title: TRIM21 promotes astrocyte-mediated neuroinflammation in experimental autoimmune encephalomyelitis by stabilizing RGMa via K33-linked ubiquitination.
    Article Snippet: .. Briefly, 200 μL of PBS solution containing 0.35 mg MOG35-55 peptide (HYP1240, MedChemExpress, NJ, USA) was added to 200 μL Freund's complete adjuvant containing 10 mg/ml mycobacterium tuberculosis (Mtb, BD, 231141, NJ, USA) and the mixture was efficiently emulsified. .. Each mouse was immunized subcutaneously adjacent to the spine with 200 μL of the emulsion (total of 175 μg MOG35-55 and 1 mg Mtb per mouse) and subsequently received an intraperitoneal injection of 200 ng pertussis toxin (PTX, 181, List Biological Labs, CA, USA) on days 0 and 2 post-immunization (total of 400 ng PTX per mouse).

    Article Title: Astrocytic TIA1‐Mediated Stress Granules Promote the Demyelination of Optic Neuritis by Sequestering mRNA of Cholesterol Synthesis Genes in an Experimental Autoimmune Encephalomyelitis Model
    Article Snippet: .. Subsequently, they received subcutaneous injections of either 200 μg of emulsified MOG35‐55 peptide (prepared in double‐distilled water, product code HY‐P1240A, MCE) or PBS, mixed in equal proportions with Complete Freund's Adjuvant (CFA) that contained 8 mg mL −1 of mycobacterium tuberculosis (H37RA strain, Difco, USA). .. Additionally, these mice were administered intraperitoneal injections of 300 ng of pertussis toxin (PTX, Sigma, dissolved in PBS) on days 0 and 2 post‐immunization.

    Article Title: TIA1‐Mediated Stress Granules Promote the Neuroinflammation and Demyelination in Experimental Autoimmune Encephalomyelitis through Upregulating IL‐31RA Signaling
    Article Snippet: .. [ ] In brief, female mice with body weights ranging from 15 to 20 g were anesthetized and subsequently immunized subcutaneously with 200 ng of emulsified MOG35‐55 peptide (dissolved in double‐distilled water, HY‐P1240A, MCE) or PBS in a 1:1 ratio with Complete Freund's Adjuvant (CFA) containing 8 mg mL −1 mycobacterium tuberculosis (H37RA strain, Difco, USA). .. Additionally, 300 ng of pertussis toxin (PTX, Sigma, dissolved in PBS) was administered intraperitoneally concurrent with the initial immunization and then again two days later.

    Article Title: TIA1-Mediated Stress Granules Promote the Neuroinflammation and Demyelination in Experimental Autoimmune Encephalomyelitis through Upregulating IL-31RA Signaling.
    Article Snippet: .. [54] In brief, female mice with body weights ranging from 15 to 20 g were anesthetized and subsequently immunized subcutaneously with 200 ng of emulsified MOG35-55 peptide (dissolved in doubledistilled water, HY-P1240A, MCE) or PBS in a 1:1 ratio with Complete Freund’s Adjuvant (CFA) containing 8 mg mL−1 mycobacterium tuberculosis (H37RA strain, Difco, USA). .. Additionally, 300 ng of pertussis toxin (PTX, Sigma, dissolved in PBS) was administered intraperitoneally concurrent with the initial immunization and then again two days later.

    Emulsion:

    Article Title: Plant defense-directed discovery of a natural anti-psoriasis agent targeting GAPDH
    Article Snippet: .. MOG35-55 peptide (amino acid sequence MEVGWYRSPFSRVVHLYRNGK-NH2, MedChemExpress, HY-P3719) dissolved in PBS at a concentration of 2 mg/mL was emulsified in an equal volume (1:1) of complete Freund’s adjuvant containing 10 mg/mL containing heat-killed Mycobacterium tuberculosis (H37Ra, Chondrex, 7027) to make an emulsion. ..



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    RGMa is upregulated in MS patients and EAE mice and localizes to astrocytes. A RGMa levels in peripheral blood samples from MS patients (n = 117) and controls (n = 50), as quantified by ELISA. B Schematic depicting the time course of <t>MOG35-55-induced</t> EAE in the murine model. C Clinical scores of EAE mice following immunization with MOG35-55 peptide (n = 12). D Representative Western blot analysis of RGMa protein expression in brain lysates from EAE mice at 28 dpi (n = 5). E Corresponding Western blot analysis of RGMa expression in spinal cord lysates from EAE mice at 28 dpi (n = 5). F Quantitative assessment of RGMa protein expression in brain lysates, normalized to GAPDH (n = 5). G Quantification of RGMa expression in spinal cord lysates, normalized to GAPDH (n = 5). H Immunofluorescence analysis illustrating the spatial distribution and co-localization of RGMa (red) with the astrocyte marker glial fibrillary acidic protein (GFAP, green) in brain and lumbar spinal cord sections between control and EAE mice at 28 dpi (n = 5). Note: IgG isotype controls confirmed staining specificity (Fig. S2). Scale bar, 50 µm. DAPI, 4',6-Diamidino-2'-phenylindole. I Inflammatory cytokine mRNA expression levels of IL-1β, IL-6, and CCL2 in primary astrocytes at 24 hours after lentivirus-mediated overexpression of RGMa or vector control
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    RGMa is upregulated in MS patients and EAE mice and localizes to astrocytes. A RGMa levels in peripheral blood samples from MS patients (n = 117) and controls (n = 50), as quantified by ELISA. B Schematic depicting the time course of <t>MOG35-55-induced</t> EAE in the murine model. C Clinical scores of EAE mice following immunization with MOG35-55 peptide (n = 12). D Representative Western blot analysis of RGMa protein expression in brain lysates from EAE mice at 28 dpi (n = 5). E Corresponding Western blot analysis of RGMa expression in spinal cord lysates from EAE mice at 28 dpi (n = 5). F Quantitative assessment of RGMa protein expression in brain lysates, normalized to GAPDH (n = 5). G Quantification of RGMa expression in spinal cord lysates, normalized to GAPDH (n = 5). H Immunofluorescence analysis illustrating the spatial distribution and co-localization of RGMa (red) with the astrocyte marker glial fibrillary acidic protein (GFAP, green) in brain and lumbar spinal cord sections between control and EAE mice at 28 dpi (n = 5). Note: IgG isotype controls confirmed staining specificity (Fig. S2). Scale bar, 50 µm. DAPI, 4',6-Diamidino-2'-phenylindole. I Inflammatory cytokine mRNA expression levels of IL-1β, IL-6, and CCL2 in primary astrocytes at 24 hours after lentivirus-mediated overexpression of RGMa or vector control
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    RGMa is upregulated in MS patients and EAE mice and localizes to astrocytes. A RGMa levels in peripheral blood samples from MS patients (n = 117) and controls (n = 50), as quantified by ELISA. B Schematic depicting the time course of <t>MOG35-55-induced</t> EAE in the murine model. C Clinical scores of EAE mice following immunization with MOG35-55 peptide (n = 12). D Representative Western blot analysis of RGMa protein expression in brain lysates from EAE mice at 28 dpi (n = 5). E Corresponding Western blot analysis of RGMa expression in spinal cord lysates from EAE mice at 28 dpi (n = 5). F Quantitative assessment of RGMa protein expression in brain lysates, normalized to GAPDH (n = 5). G Quantification of RGMa expression in spinal cord lysates, normalized to GAPDH (n = 5). H Immunofluorescence analysis illustrating the spatial distribution and co-localization of RGMa (red) with the astrocyte marker glial fibrillary acidic protein (GFAP, green) in brain and lumbar spinal cord sections between control and EAE mice at 28 dpi (n = 5). Note: IgG isotype controls confirmed staining specificity (Fig. S2). Scale bar, 50 µm. DAPI, 4',6-Diamidino-2'-phenylindole. I Inflammatory cytokine mRNA expression levels of IL-1β, IL-6, and CCL2 in primary astrocytes at 24 hours after lentivirus-mediated overexpression of RGMa or vector control
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    RGMa is upregulated in MS patients and EAE mice and localizes to astrocytes. A RGMa levels in peripheral blood samples from MS patients (n = 117) and controls (n = 50), as quantified by ELISA. B Schematic depicting the time course of <t>MOG35-55-induced</t> EAE in the murine model. C Clinical scores of EAE mice following immunization with MOG35-55 peptide (n = 12). D Representative Western blot analysis of RGMa protein expression in brain lysates from EAE mice at 28 dpi (n = 5). E Corresponding Western blot analysis of RGMa expression in spinal cord lysates from EAE mice at 28 dpi (n = 5). F Quantitative assessment of RGMa protein expression in brain lysates, normalized to GAPDH (n = 5). G Quantification of RGMa expression in spinal cord lysates, normalized to GAPDH (n = 5). H Immunofluorescence analysis illustrating the spatial distribution and co-localization of RGMa (red) with the astrocyte marker glial fibrillary acidic protein (GFAP, green) in brain and lumbar spinal cord sections between control and EAE mice at 28 dpi (n = 5). Note: IgG isotype controls confirmed staining specificity (Fig. S2). Scale bar, 50 µm. DAPI, 4',6-Diamidino-2'-phenylindole. I Inflammatory cytokine mRNA expression levels of IL-1β, IL-6, and CCL2 in primary astrocytes at 24 hours after lentivirus-mediated overexpression of RGMa or vector control
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    RGMa is upregulated in MS patients and EAE mice and localizes to astrocytes. A RGMa levels in peripheral blood samples from MS patients (n = 117) and controls (n = 50), as quantified by ELISA. B Schematic depicting the time course of <t>MOG35-55-induced</t> EAE in the murine model. C Clinical scores of EAE mice following immunization with MOG35-55 peptide (n = 12). D Representative Western blot analysis of RGMa protein expression in brain lysates from EAE mice at 28 dpi (n = 5). E Corresponding Western blot analysis of RGMa expression in spinal cord lysates from EAE mice at 28 dpi (n = 5). F Quantitative assessment of RGMa protein expression in brain lysates, normalized to GAPDH (n = 5). G Quantification of RGMa expression in spinal cord lysates, normalized to GAPDH (n = 5). H Immunofluorescence analysis illustrating the spatial distribution and co-localization of RGMa (red) with the astrocyte marker glial fibrillary acidic protein (GFAP, green) in brain and lumbar spinal cord sections between control and EAE mice at 28 dpi (n = 5). Note: IgG isotype controls confirmed staining specificity (Fig. S2). Scale bar, 50 µm. DAPI, 4',6-Diamidino-2'-phenylindole. I Inflammatory cytokine mRNA expression levels of IL-1β, IL-6, and CCL2 in primary astrocytes at 24 hours after lentivirus-mediated overexpression of RGMa or vector control
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    Image Search Results


    RGMa is upregulated in MS patients and EAE mice and localizes to astrocytes. A RGMa levels in peripheral blood samples from MS patients (n = 117) and controls (n = 50), as quantified by ELISA. B Schematic depicting the time course of MOG35-55-induced EAE in the murine model. C Clinical scores of EAE mice following immunization with MOG35-55 peptide (n = 12). D Representative Western blot analysis of RGMa protein expression in brain lysates from EAE mice at 28 dpi (n = 5). E Corresponding Western blot analysis of RGMa expression in spinal cord lysates from EAE mice at 28 dpi (n = 5). F Quantitative assessment of RGMa protein expression in brain lysates, normalized to GAPDH (n = 5). G Quantification of RGMa expression in spinal cord lysates, normalized to GAPDH (n = 5). H Immunofluorescence analysis illustrating the spatial distribution and co-localization of RGMa (red) with the astrocyte marker glial fibrillary acidic protein (GFAP, green) in brain and lumbar spinal cord sections between control and EAE mice at 28 dpi (n = 5). Note: IgG isotype controls confirmed staining specificity (Fig. S2). Scale bar, 50 µm. DAPI, 4',6-Diamidino-2'-phenylindole. I Inflammatory cytokine mRNA expression levels of IL-1β, IL-6, and CCL2 in primary astrocytes at 24 hours after lentivirus-mediated overexpression of RGMa or vector control

    Journal: Journal of Neuroinflammation

    Article Title: TRIM21 promotes astrocyte-mediated neuroinflammation in experimental autoimmune encephalomyelitis by stabilizing RGMa via K33-linked ubiquitination

    doi: 10.1186/s12974-026-03769-4

    Figure Lengend Snippet: RGMa is upregulated in MS patients and EAE mice and localizes to astrocytes. A RGMa levels in peripheral blood samples from MS patients (n = 117) and controls (n = 50), as quantified by ELISA. B Schematic depicting the time course of MOG35-55-induced EAE in the murine model. C Clinical scores of EAE mice following immunization with MOG35-55 peptide (n = 12). D Representative Western blot analysis of RGMa protein expression in brain lysates from EAE mice at 28 dpi (n = 5). E Corresponding Western blot analysis of RGMa expression in spinal cord lysates from EAE mice at 28 dpi (n = 5). F Quantitative assessment of RGMa protein expression in brain lysates, normalized to GAPDH (n = 5). G Quantification of RGMa expression in spinal cord lysates, normalized to GAPDH (n = 5). H Immunofluorescence analysis illustrating the spatial distribution and co-localization of RGMa (red) with the astrocyte marker glial fibrillary acidic protein (GFAP, green) in brain and lumbar spinal cord sections between control and EAE mice at 28 dpi (n = 5). Note: IgG isotype controls confirmed staining specificity (Fig. S2). Scale bar, 50 µm. DAPI, 4',6-Diamidino-2'-phenylindole. I Inflammatory cytokine mRNA expression levels of IL-1β, IL-6, and CCL2 in primary astrocytes at 24 hours after lentivirus-mediated overexpression of RGMa or vector control

    Article Snippet: After 10 days of induction with MOG35-55 by which time mice gradually exhibited tail weakness, the mice were randomly assigned to receive daily intraperitoneal injections of either Quisinostat (HY-12726, MedChemExpress, USA) at 10 mg/kg or an equal volume of vehicle control for 2 weeks.

    Techniques: Enzyme-linked Immunosorbent Assay, Western Blot, Expressing, Immunofluorescence, Marker, Control, Staining, Over Expression, Plasmid Preparation